PROFIL DISOLUSI DAN PENETAPAN KADAR TABLET MELOKSIKAM INOVATOR DAN GENERIK BERMEREK DENGAN KCKT (KROMATOGRAFI CAIR KINERJA TINGGI)

D. Mutiatikum, Mariana Raini

PROFIL DISOLUSI DAN PENETAPAN KADAR TABLET MELOKSIKAM INOVATOR DAN GENERIK BERMEREK DENGAN KCKT (KROMATOGRAFI CAIR KINERJA TINGGI)

Abstract


Abstract. The determination of meloxicam and the dissolution test has been done. Drug dissolution test is an approach to evaluate drug release characteristics of product (Tablets/capsules) in vitro. The tests are conducted for various durations from 5,10,15,20,25,30,40,50 and 60 minutes with appropriate sampling. The method of dissolution test and assay of meloxicam accords with British Pharmacopoeia 2007. A control  experiment wih HPLC was performed simoultaneously. The dissolution test of meloxicam at 30 minutes in tablet A is 97.79% and tablet B is 87.78% meet the requirement of the British Pharmacopoeia 2007. The content of meloxicam are in tablet A is 100.26%, tablet B is 104.07%. Both of its meet the requirement of British Pharmacopoeia 2007. The content of meloxicam are in tablet A is 100.26%, tablet B is 104.07%. Both of its meet the requirement of British Pharmacopoeia 2007.

Key Words : Meloksikam, KCKT


Keywords


Meloksikam; KCKT

Full Text: PDF

Refbacks

  • There are currently no refbacks.



Buletin Penelitian Kesehatan (Bulletin of Health Research, p-ISSN: 0125-9695. e-ISSN: 2338-3453) is published by Badan Penelitian dan Pengembangan Kesehatan, Ministry of Health of Republic of Indonesia
Main Indexing :

More...
Visitor Number : View BPK Statistics
Creative Commons License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.